Otrivin nasal spray | uses, dosage, and side effects

Otrivin nasal spray

Otrivin nasal spray has many uses as it relieves nasal congestion caused by sinusitis in various colds.

Stay tuned for more information on the uses, contraindications, and dosage of Otrivin nasal spray in this article.


Otrivin nasal spray active ingredient

Xylometazoline Hydrochloride 0.1%.


Pharmacological form

It is a nasal spray containing a clear, colorless aqueous solution.


Drug concentrations

There are two concentrations of Otrivin:

  • Otrivin 0.1% spray for adults.
  • Otrivin 0.05% spray for children.


How Otrivin spray works?

Otrivin 0.1% nasal spray removes nasal congestion quickly and effectively within 2 minutes and lasts up to 12 hours by:


  • Reducing mucous membrane inflammation.
  • Preventing stuffy nose.
  • Clearing the sinuses of mucus.
  • Facilitating the process of breathing through the nose.


How to use Otrivin nasal spray?

Otrivin spray is used in a specific way to make the most of the solution by performing the following steps:

  • Clean the nose well.
  • Place in an upright position and apply pressure to the pump to distribute the medication evenly into the nose.
  • Breathe in slowly, inhale the medicine and repeat the process with the other nostril.
  • Do not clean the nose immediately after using the spray to allow absorption.


Otrivin nasal spray uses

Otrivin nasal spray has many uses in multiple cases that result in nasal congestion and the accumulation of mucus that obstructs breathing and gives a feeling of discomfort, and here are some of these cases:

Nasal spray for cold

Otrivin is used for nasal congestion during colds, as it reduces the size of the blood vessels, facilitates the entry of air through the nostrils, and gives a feeling of comfort and natural breathing.

Allergy nasal spray

Otrivin sinus spray treats nasal congestion and inflammation in people with chronic or seasonal allergies.

It reduces nasal itching and gives a feeling of comfort.


Otrivin nasal spray dosage

otrivin nasal spray dosage

Otrivin treats nasal congestion in the following dosage:


  • A spray is used in the nostrils 3 to 4 times a day.
  • Do not use longer than one week without consulting a doctor.
  • Adults and adolescents aged 12 and up may use this product.


What are the side effects of Otrivin nasal spray?

The use of Otrivin Spray may cause some side effects, but they are not dangerous, such as:

  • Temporary burning and dry nose.
  • Runny nose and sneezing.

Side effects may develop in some rare cases, and a doctor should be consulted immediately if any of these symptoms appear.

  • Skin rash.
  • Itching.
  • Swelling of the tongue, throat, or face.
  • Severe dizziness.
  • Breathing difficulty.


Otrivin pediatric nasal spray

Otrivin spray ( 0.05%); decongests the nose, reduces pressure on the blood vessels in the mucous membranes, and facilitates breathing through the nose.


Otrivin spray contraindications

The use of Otrivin spray is limited to people who do not suffer from health problems that may worsen when using it, for example:

  • Xylometazoline hydrochloride hypersensitivity.
  • Allergies to different decongestants.
  • Children under 12 years old.
  • Brain or nerve surgery.
  • Pituitary gland excision through the nose, after exposing the dura mater, after performing some surgeries through the nose or mouth.
  • Dry and atrophic rhinitis.
  • Closed-angle glaucoma.


Disadvantages of using Otrivin for a long time

Otrivin nasal spray rebound congestion may occur upon long-term use.

Do not use it for longer than 3 to 5 days.


Warnings and precautions

Some instructions must be followed when using Otrivin nasal spray to avoid potential complications, such as:

  • Do not use an Otrivin inhaler more than two to three times daily, every 8 to 10 hours.
  • Do not use it for longer than 3 to 5 days.
  • It is contraindicated for those who suffer from the following health problems:
  • Excessive thyroid gland activity.
  • Diabetes.
  • Pheochromocytoma.
  • Prostate tumors.
  • Cardiovascular patients and patients with high blood pressure.
  • Those using a monoamine oxidase (MAO) inhibitor or those who have taken them 14 days before.
  • Glaucoma or high intraocular pressure.


Otrivin nasal spray for pregnant and lactating women

Otrivin Spray should be used under medical supervision during pregnancy because of its vasoconstrictor effect; Which may cause health problems.

Also, no studies confirm the excretion of the active substance in breast milk during lactation.

However, you should consult your doctor before use.


Drug interactions

The active ingredient in Otrivin spray can interact with some of the following medicines:

Tricyclic antidepressants

The combination of tricyclic antidepressants and sympathomimetics increases the sympathetic effect of the active substance xylometazoline, so they should not be used together.

Monoamine oxidase (MAO) inhibitors

Otrivin’s active ingredient stimulates the action of enzyme inhibitors, resulting in increased blood pressure.


Storage method

Store away from heat at a temperature not exceeding 30°C.

Also, keep out of reach of children.


The price of Otrivin spray in some Arab countries

The price of Otrivin spray in Egypt is 10.25 EGP.

Also, Otrivin nasal spray price in KSA is 13.80 SAR.

Otrivin nasal spray price UAE is 1.160 Kuwaiti dinars.


Otrivin nasal spray for covid patients

Corona (COVID-19) is the disease of the era that has killed nearly 1.5 million people, and its principal cause is the SARS virus (SARS CoV 2).

Most people infected with the Coronavirus develop respiratory disease, and some may not show symptoms of the disease, while others have severe symptoms.

The Coronavirus is also spread from person to person via droplets expelled by the patient when he coughs, sneezes, or speaks.

Therefore, Otrivin spray is an effective way to treat rhinitis and sinus infections.

It also has a role in reducing viral infections transmitted through droplets. 

It helps to get rid of the accumulated mucus in the nose that comes out with coughing or sneezing.


Can I use Otrivin nasal spray if I have covid-19?

Otrivin helps reduce the chances of infection by getting rid of the mucus that carries the virus.

It also reduces the viral load of the infected person.

Reduces the secondary bacterial load, thus reducing the incidence of complications.

It also relieves nasopharyngitis in people infected with the new SARS virus.



In conclusion, Otrivin spray has many uses, but it also has risks and side effects.

Misuse or dependence for a long time leads to unwanted adverse effects such as nasal irritation, allergy, or loss of smell.

In addition, it may lead to the death of beneficial microorganisms in the nose that protects the body from infection.


Read Also;

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Translated by
Dr. Basant Mohamed Atef

Translator. Dr. Basant Atef

I am a pharmacist with a Ph.D. in microbiology. Passionate about delivering medical sciences to others. I love explaining and researching medical information in both Arabic and English. It always bothered me that medical information in Arabic is so scarce, so I took it upon myself to help change that. So, I specialized in SEO medical content writing as well as medical translation. When I am not working on that, you’ll find me out exploring the world with my two wonderful boys.
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